downstream_gene_variant downstream_gene_variant downstream_gene_variant downstream_gene_variant downstream_gene_variant downstream_gene_variant downstream_gene_variant downstream_gene_variant downstream_gene_variant downstream_gene_variant downstream_gene_variant downstream_gene_variant downstream_gene_variant downstream_gene_variant intron_variant non_coding_transcript_variant downstream_gene_variant upstream_gene_variant downstream_gene_variant downstream_gene_variant downstream_gene_variant downstream_gene_variant downstream_gene_variant